For immediate, free, and confidential assistance, download or. The imaging features at mri and ultrasound of cases of adiposis dolorosa nine female, four male. Adiposis dolorosa, or dercums disease is a rare condition characterized by multiple, painful lipomas, or small benign fatty tumors. This is dercums disease also dercum disease or adiposis dolorosa, first identified by francis x. Dercums disease or adiposis dolorosatypescausessymptoms. The sleep disorder and other pains may be a part of the adiposis dolorosa rating as it is a part of the illness. Adiposis dolorosa ad, or dercum disease, is a rare disorder that was first described in 1888 and characterized by the national organization of rare disorders. Her clinical history and histopathologic data suggested adiposis dolorosa dercums disease. Adiposis dolorosa is a syndrome of symptoms associated with fat metabolism and was first described by dercum in 1892 from a case in the wards of a philadelphia hospital. Apr 30, 2012 we propose the minimal definition of dercums disease to be generalised overweight or obesity in combination with painful adipose tissue. The aim of this study was to describe ultrasound and magnetic resonance imaging mri features of adiposis dolorosa, dercums disease, and to evaluate the mri features prospectively against a large number of mri examinations. Dercums disease adiposis dolorosa, abstract among the symptoms reported by patients undergoing breast imaging, pain is one of the most common.
It exists as a separate entity that must be distinguished from other causes of knee pain. These fatty growths form under the skin subcutaneous and feel like firm nodules and are typically. Mar 20, 2015 posts about medical research written by cprentice1208. Im posting here out of concern for one of my family members.
This page lists the people with confirmed diagnosis of dercums disease, also known as adiposis dolorosa. For language access assistance, contact the ncats public information officer. Adiposis dolorosa, anders syndrome, dercumvitaut syndrome, lipalgia, adiposalgia, lipomatosis dolorosa of the legs, lipohypertrophy dolorosa, painful column leg, painful lipedema syndrome. The site of the presystolic activation and delayed conduction along the reentrant circuit have been shown to have significant abnormalities such as fibrosis, adiposis, and degeneration of the myocardium. Lipomas are the most common benign neoplasms of mesenchymal origin and may arise in any location where fat is normally present. Adiposis dolorosa, also known as anders disease or dercums disease, is a rare disease characterized by multiple painful lipomas that arise in adult life. Adiposis dolorosa dercums disease is a rare, sporadic disease characterised by generalised obesity with pronounced pain in the adipose tissue. The most common sites are the knees referred to as juxtaarticular adiposis dolorosa, upper thighs, back and upper arms. Adiposis dolorosa genetic and rare diseases information center. Files are available under licenses specified on their description page.
Adiposis dolorosa most commonly appears between age of 3550 years, women are more prone to dercum disease than man, and the condition mainly affects postmenopausal woman, it is five to thirty times more common in women. In the united states, a rare disease is generally considered to be a disease that affects fewer than 200,000 people. Surveys of current sufferers seem to indicate that the disease causes the obesity. Adiposis dolorosa is a rare condition characterized by the growth of multiple, painful, lipomas benign, fatty tumors. The subjective pain sensation was evaluated with a visual analog scale and number of words chosen, and the objective pain sensation with the mechanical pressure pain threshold. The main symptoms of dercums disease, according to the early reports, are obesity and painful adipose tissue.
Mystery diagnosis the man with 100 lumps dercums disease aka. Cureus exophytic adiposis dolorosa dercums disease of. Source national institutes of health nih ophanet, a consortium of european partners, currently defines a condition rare when it affects 1 person per 2,000. Adiposis dolorosa should be diagnosed through physical. Adiposis dolorosa dercum disease usually occurs in adults, and women are more commonly affected than men. We hereby report a case of type iii dercums disease in view of the rarity of this condition. Dercums disease adiposis dolorosa is an unusual progressive syndrome of unknown etiology characterized by multiple painful lipomas that arise in adult life, most often affecting postmenopausal women who are obese. These adiposes are etiologically divisible into two types. Pdf adiposis dolorosa of scalp presenting with severe headache. If you have problems viewing pdf files, download the latest version of adobe reader. The associated symptoms in dercums disease include fatty deposits, easy bruisability, sleep disturbances, impaired memory, depression, difficulty concentrating, anxiety, rapid heartbeat, shortness of breath, diabetes, bloating, constipation, fatigue. Dercums disease, or adiposis dolorosa, is a rare entity, characterized by overweight or obesity and the appearance of multiple painful lipomas. Media in category adiposis dolorosa this category contains only the following file. Review article open access adiposis dolorosa a scientific.
Relief was maximum 20 minutes after the end of drug infusion. Article on dercums disease imaging mriultrasound update. If one is to judge from the number of cases reported in the literature, adiposis dolorosa is a rather rare disease. Like fibromyalgia, the diagnosis of dercum disease adiposis dolorosa is made clinically, and both diseases include symptoms of a number of associated diseases. Adiposis dolorosa dercum, anders disease updated 2018 dercums disease. Dercums disease adiposis dolorosa, or lipomatous dolorosa morbus dercum was first described by the american neurologist francis dercum in 1888. Dercums disease adiposis dolorosa is a rare condition characterized by progressively painful fatty deposits, usually, in menopausal women with obesity, asthenia and mental phenomena. It would seem that the infrequent occurrence of the disease is more apparent than real.
Dercums disease diagnosis registry no one seems to know how many dercum diagnoses there are in the united states and other parts of the world, so we decided to start a registry that is somewhat anonymous. Here are links to possibly useful sources of information about adiposis dolorosa. Adiposis dolorosa is rare and to our knowledge, the prevalence in the united states or worldwide has not been established. However, in dercum disease adiposis dolorosa, a relationship exists between pain and body weight, with pain in the fatty tissue and obesity being fundamental criteria for the diagnosis of dercum. Dercum disease also known as adiposis dolorosa, anders syndrome and dercumvitaut syndrome is a rare condition that is characterized by multiple, painful fatty lipomas benign, fatty tumors that occur chiefly in postmenopausal, obese women of middle age. These deposits characteristically are located on the face, the nuchal and truncal areas, and episternally, as well as in the mediastinum and epicardium. The cause and mechanism of dercums disease remains unknown. However, although it is 20 times more common in women, 16 percent of the reported. Mastalgia is generally classified as cyclic, noncyclic, or extramammary. Consideration of special clinical varieties or syndromesgroups of cases.
Dercums disease nord national organization for rare disorders. All structured data from the file and property namespaces is available under the creative commons cc0 license. Adiposis dolorosa ad is a rare disorder of painful nodular subcutaneous fat accompanied by fatigue, difficulty with weight loss, inflammation, increased fluid in adipose tissue lipedema and. Adiposis dolorosa dercum, anders disease statpearls ncbi. Adiposis dolorosa medigoo health tests and free medical. Adiposis dolorosa is a rare disorder affecting fatty tissue under the skin. Get a printable copy pdf file of the complete article 558k, or click on a page image below to browse page by page. Adiposis dolorosa, also known as dercums disease 1 or anders disease, is a rare condition characterized by generalized obesity and fatty tumors in the adipose tissue. Adiposis dolorosa is a rare condition characterized by the growth of multiple. Older medical literature states that the disease occurs most often in obese postmenopausal women, but can also occur in men.
Dercum disease medigoo health tests and free medical. The scattered myocyte islets in the extensive adiposis andor fibrosis can form an electrical maze around the surgical suture area. Close this message to accept cookies or find out how to manage your cookie settings. Adiposis dolorosa symptoms, diagnosis, treatments and causes. It is also known as dercum disease, ander syndrome, morbus dercum. Genetic and rare diseases information center gard po box 8126, gaithersburg, md 208988126 tollfree. Corticosteroidinduced juxtaarticular adiposis dolorosa. Greenbaum, md, john varga, md \sb\longterm treatment with high doses of corticosteroids leads to the development of truncal obesity and focal fatty deposition.
Adiposis dolorosa, also known as dercums disease or anders disease, is a rare condition characterized by generalized obesity and fatty tumors in the adipose tissue. Adiposis dolorosa is a rare disorder of multiple painful subcutaneous growths of. Her systemic symptoms included generalized weakness, fatigue, memory impairment, and arthralgias. This condition occurs most often in women who are overweight or obese, and signs. Pathophysiology the understanding of the mechanism and pathogenesis of adiposis dolorosa was unknown. This condition occurs most often in women who are overweight or obese, and signs and symptoms typically appear between ages 35 and 50. The pain is most commonly described by the patients as burning or aching. Adiposis dolorosa or dercums disease is an extremely rare disease with characteristic painful lipomas. A rare cause of breast pain is dercums disease, or adiposis dolorosa, a condition characterized by multiple, often painful subcutaneous lipomas. A rare cause of breast pain is dercums disease, or adiposis dolorosa, a condition characterized by multiple, often painful subcutaneous. The disease is characterized by painful fatty tumors andor fatty deposits. A forum and community offering information, a few other names used for dercums disease are adiposis dolorosa, adiposa dolorosa, lipomatosis dolorosa.
Know the types, causes, symptoms, treatment, pathophysiology, epidemiology, prevention and prognosis of dercums disease or adiposis dolorosa. Intractable pain in a patient with adiposis dolorosa dercums disease was treated by iv administration of lidocaine 200 to 400 mg. Various areas of the body may swell for no apparent reason. These types of articles are always helpful to physicians or medical personnel unfamiliar with dd. Dercums disease articleslinks part i dercums disease. Get a printable copy pdf file of the complete article 197k, or click on a page image below to browse page by page. Dercums disease or adiposis dolorosa abstract dercums disease dd, also called adiposis dolorosa ad, is known as a rare, chronic and progressive disorder characterized by multiple, subcutaneous painful adipose tissue masses. Adiposis dolorosa was first described in 1892, by dercum, who named the disease adiposis dolorosa to describe the painful adiposities fat accumulations seen in his 3 patients. The pain may disappear without treatment but any manual therapy such as. Dercums disease adiposis dolorosa volume 1 issue 2 p. Dercums disease is a predominantly female disease occurring between the ages of 3550 years. Juxtaarticular adiposis dolorosa may be defined as the localised accumulation of painful fat near joints, most commonly the knee. The understanding of the cause and mechanism of dercum disease remains unknown. Adiposis dolorosa varicose veins nyc nj spider veins.
Dec 15, 2017 first described in 1892 by the american neurologist francis xavier dercum at jefferson medical college in philadelphia, pennsylvania, dercum disease adiposis dolorosa is an unusual progressive syndrome of unknown etiology characterized by multiple painful lipomas that arise in adult life, most often affecting obese postmenopausal women. Dercums disease as a cause of weight loss failure after. A new casereport bouchra amine, fabienne leguilchard, claude laurent benhamou 6 february 2004. Subjects were white, nonhispanic except for 3 hispanics and 2 african americans, and mostly women 82. Sep 20, 2015 talk to your vso, the depression should be secondary to the pain of the adiposis dolorosa. She 33f has graves disease and dercums, both separately causing a lot of secondary disorders like ibs and ocular migraine, and she has been living with us for 3 years now because living by herself was no longer possible. Lipomas in people with dercums disease may be found in any part of the body. Pain was examined preoperatively and at 3 months, and 1, 2, 3, and 5 years after liposuction. Dercums is a rare disease that causes painful, fatty growths to appear under the skin, sometimes all over the body.
Adiposis dolorosa, also known as dercums disease, is characterized by painful lipomas that usually appear on the trunk and upper and lower proximal extremities. Dercums disease adiposis dolorosa diagnosis registry. These lipomas mainly occur on the trunk, the upper arms and upper legs. Approximately 250 cases have been described in the worlds literature since the original report of the condition by dercum in 1888.
Fariya rasheed department of dermatology, apollo hospital, hyderabad, india. Pdf a 46yearold female, known case of adiposis dolorosa since adolescence, noticed painful thickening of scalp in bilateral parietooccipital areas. Dercum disease adiposis dolorosa has been classified by the world health organization who as a distinct entity. This entity was first described by francis xavier dercum in 1862. Ideal sources for wikipedias health content are defined in the guideline wikipedia. Adiposis dolorosa is chronic and tends to be progressive. Chronic pain is the cardinal symptom and is characterized as aching burning and stabbing. Get a printable copy pdf file of the complete article 937k, or click on a page image below to browse page by page.
Dd mainly occurs in overweight or obese adults, mostly postmenopausal women. If you try and claim them as due to the gulf war under section 3. Possible causes ranges from tissue trauma to congenital. This site provides links to research published in peer. Adiposis dolorosa is more than painful fat request pdf. Interferon alfa2b induced longterm relief of pain in two patients with adiposis dolorosa and chronic hepatitis. Case of adiposis dolorosa dercums disease sage journals. Dercum, a neurologist in pennsylvania, in 1892, and bears his name. Below is a link to a newly published article in the medical journal, clinical radiology. The tumors are normally painful and found in multiples on the extremities. Adiposis dolorosa is a condition characterized by painful folds of fatty adipose tissue or the growth of multiple benign noncancerous fatty tumors called lipomas. Im a bit late getting this info on the site here due to life getting in the way, but here is a research article link titled an abnormal lymphatic phenotype is associated with subcutaneous adipose tissue deposits in dercums disease. Adiposis dolorosa genetic and rare diseases information. It is a rare disease more common in obese postmenopausal women.
Apr 06, 2018 dercums disease or adiposis dolorosa is a chronic as well as progressive condition in which benign tumors of lipids called lipomas develop in the torso and the extremities that lie close to the torso of the body. A diposis dolorosa ad, or dercum disease, is a rare disorder that was first described in 1888 and characterized by the national organization of rare disorders nord as a chronic pain condition of the adipose tissue generally found in patients who are overweight or obese. Review of dercums disease and proposal of diagnostic. The national organization of rare diseases nord notes, dercum disease is a rare disorder in which there are fatty deposits which apply pressure to the nerves, resulting in weakness and pain. Adiposis dolorosa pain management dercums disease research. Adiposis dolorosa dercums disease dermatology advisor. The tumors can be encapsulated or the fatty deposits can be diffuse. Traumainduced adiposis dolorosa dercums disease bmj. Dercums disease articleslinks part i posted on may 28, 2012 by cprentice1208 comments off on dercums disease articleslinks part i dercums disease adiposis dolorosa.385 942 861 1414 1240 434 666 911 868 449 167 288 853 1571 349 37 417 1166 899 1225 477 553 1538 303 1193 1516 616 1254 801 1083 413 178 351 319 1266